Solaray - ProSorb Ashwagandha 18x

Solaray ProSorb Ashwagandha 18X 240mg

Solaray ProSorb Ashwagandha 18X is a single-ingredient ashwagandha supplement built entirely around Shoden® — a clinically studied, proprietary extract from Arjuna Natural standardized to 35% withanolide glycosides, the most bioavailable form of ashwagandha's active compounds. At 240mg per VegCap, each serving delivers 84mg of withanolide glycosides, and clinical data show Shoden absorbs 18 times more effectively than a standard 2.5% withanolide extract, making it one of the most potent ashwagandha products available per milligram of dose.

At a Glance

• Serving size: 1 VegCap | Servings per container: 30
• Shoden® Ashwagandha (root and leaf extract): 240mg
• Withanolide Glycosides: 84mg (35% standardization)
• 18X absorption vs. standard 2.5% withanolide extract
• Backed by 9 published clinical studies
• Vegan | Gluten-free | Made without soy | LLabverified
• Other ingredients: Cellulose, Vegetable Cellulose Capsule, Silica

Why Shoden® Is Different from Standard Ashwagandha

Most ashwagandha supplements are standardized to total withanolide content — typically 2.5% to 5% — without distinguishing between withanolide types. A 2025 clinical study published in Current Therapeutic Research identified withanolide glycosides — not total withanolides — as the primary drivers of bioavailability and absorption in ashwagandha extracts. Shoden® is standardized specifically to 35% withanolide glycosides. This water-soluble form enters systemic circulation most efficiently, resulting in markedly higher blood levels and a longer half-life compared to conventional extracts.

In head-to-head pharmacokinetic testing against four standardized commercial ashwagandha extracts, Shoden® demonstrated significantly higher C-max (peak blood concentration), longer mean residence time, and lower systemic clearance — confirming that its active compounds stay in circulation longer and reach higher concentrations than alternatives dosed at equivalent withanolide totals. This is what the "18X absorption" claim reflects: 18 times greater bioavailability than a standard 2.5% withanolide extract, as confirmed by human clinical data.

What Shoden® Supports — Clinical Evidence

• Stress and cortisol: Published research demonstrates that Shoden® at 60–120mg effectively reduces morning serum cortisol levels — the primary hormonal marker of chronic stress — by regulating the hypothalamus-pituitary-adrenal (HPA) axis.
• Mood and anxiety: A randomized controlled trial (PubMed, 2024) confirmed that Shoden® at 60mg and 120mg significantly reduced perceived stress and anxiety scores compared to placebo.
• Testosterone: The same RCT demonstrated a significant increase in total testosterone levels alongside a reduction in cortisol — consistent with the established inverse relationship between chronic cortisol elevation and testosterone production.
• Sleep: Shoden® supports relaxation and sleep quality through upregulation of the GABA neurotransmitter — one of its documented mechanisms of action, alongside HPA axis modulation.
• Immune health and cognition: Among the 9 published studies on Shoden®, research has shown improvements in immune cell markers, cognitive function, and reduced oxidative stress.

Supplement Facts

Other Ingredients: Cellulose, Vegetable Cellulose Capsule, Silica.

No: Soy • Gluten • Animal-derived ingredients • Artificial additives

Directions & Use

• Dose: Take 1 VegCap daily with a glass of water.
• Timing: Can be taken in the morning or evening. For sleep and relaxation support, evening use is commonly preferred. For stress management and cortisol reduction, morning use aligns with the cortisol awakening response.
• Consistency: Ashwagandha's adaptogenic benefits accumulate with consistent daily use over 4–8 weeks — single-dose effects are mild; the primary benefits are realized through sustained supplementation.
• Storage: Store in a cool, dry place. Keep out of reach of children.
• Caution: Keep your licensed healthcare practitioner informed when using this product. Do not use if pregnant.

About Solaray

Founded in 1973, Solaray is one of the longest-standing supplement brands in the natural health industry. Their ProSorb line applies the latest bioavailability science to single-ingredient supplements — using clinically studied, branded ingredient forms with documented absorption advantages over commodity equivalents. Every Solaray product is lab-verified for potency, purity, and identity.

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