Swiss Chems - MK-677 (Ibutamoren) Capsules

MK-677, also known as Ibutamoren, is a non-peptide growth hormone secretagogue that mimics ghrelin's action to stimulate growth hormone and IGF-1 release. This product from SwissChems provides 10mg per capsule in a bottle of 60 capsules, intended strictly for research purposes.

MK-677 is not a dietary supplement. It is a research chemical not approved by the FDA for human consumption. All information below is for educational and research reference only.

Research Context

MK-677 (Ibutamoren) is an orally active, non-peptidyl agonist of the ghrelin receptor (GHSR). In preclinical and clinical research, it has been studied for its ability to increase secretion of growth hormone (GH) and insulin-like growth factor 1 (IGF-1) without affecting cortisol levels.

Published Research Findings

• Growth Hormone & IGF-1 Elevation: Studies show MK-677 at 25mg daily increases mean 24-hour GH secretion by up to 97% and IGF-1 by up to 60% after 2 weeks of administration.
• Body Composition: Research demonstrates increases in lean body mass (up to 3kg over 2 months) and fat-free mass in elderly subjects.
• Bone Density: Long-term studies (up to 2 years) show improvements in bone mineral density in elderly populations.
• Sleep Architecture: Research indicates enhanced REM sleep duration and slow-wave sleep.

Mechanism of Action

MK-677 binds to the ghrelin receptor in the hypothalamus and pituitary gland, triggering pulsatile GH release similar to endogenous ghrelin. Unlike injectable GHRPs, it is orally bioavailable with a half-life of approximately 24 hours, allowing once-daily dosing in research protocols.

Product Specifications

Common Research Dosing Protocols

The following protocols are compiled from published research studies for educational purposes only. This product is not for human consumption.

• Standard Research Dose: 10–25mg daily, taken orally once per day
• Study Duration: 2 weeks to 2 years, depending on research objective
• Timing: Often administered in the evening to align with natural GH pulses
• Cycling: Some protocols include 8–12 weeks on, 4 weeks off; others are continuous for 1–2 years

Reported Research Side Effects

Published studies note the following side effects in research subjects:

• Increased appetite (most common)
• Transient water retention
• Mild numbness/tingling in extremities
• Elevated fasting blood glucose in some subjects

Regulatory Status

• FDA Status: Not approved as a dietary supplement. Sold as a research chemical only.
• WADA Status: Prohibited under S2.2 Peptide Hormones, Growth Factors, Related Substances, and Mimetics.
• Sport Testing: Detectable in urine testing; use in tested sports will result in a positive test.
• Legal Status: Legal for research purchase in most jurisdictions; not approved for human therapeutic use.

Storage & Handling

• Store at room temperature (59–86°F / 15–30°C)
• Keep the container tightly closed
• Protect from light and moisture
• Do not refrigerate

Important Disclaimer

This product is intended strictly for laboratory research purposes. It is not intended for human consumption. All information provided is for educational purposes only and does not constitute medical advice. Consult a qualified healthcare professional before considering any supplement or research chemical for personal use.

SwissChems products are not dietary supplements and are not approved by the FDA for human consumption. Buyers assume all risk and responsibility associated with research use.